Global Burden of Disease (GBD)

The GBD study is the largest and most comprehensive effort to quantify health loss across places and over time, so health systems can be improved and disparities eliminated.

607 billion+ highly standardized and comprehensive estimates measure health outcomes and systems.
459 health outcomes and risk factors provide a powerful basis for insights on global health trends and challenges.
204 countries and territories, plus dozens of subnational locations show trends at regional, national, and local levels.
12,000 individuals from over 160 countries and territories collaborate in vetting GBD data sources and estimates.

Key findings from GBD 2021

Our most recent GBD estimates were released in 2024, incorporating data through 2021. These findings provide new insights on the seismic shift in health trends due to the COVID-19 pandemic.

Figure 1: Life expectancy declined in 84% of countries and territories during the COVID-19 pandemic. 

Between 1950 and 2021, global life expectancy increased by almost 23 years from 49 to 71.7 years. But it declined by 1.6 years between 2019 and 2021.

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Finding 2: By 2100, fertility rates will not be high enough to sustain population growth over time in 97% of countries and territories.

Researchers anticipate a massive shifting of births from high-income countries to low-income countries. Unless countries facilitate ethical immigration, populations are expected to contract in areas where fertility is below 2.1 children per person who could give birth.

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GBD 2021 infographics

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Forecasts of disease burden through 2050

Our forecasts reveal that life expectancy will continue to increase everywhere, indicating a radically different future than many experts have predicted, even after factoring in rising temperatures.

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Disease burden: successes and challenges

Since 2010, the world succeeded in halving the burden of many diseases such as HIV/AIDS and diarrhea and slashing the disease burden from injuries by a quarter after accounting for differences in age and population size across countries.